LKT Labs

Biochemicals for Life Science Research

Teicoplanin

Teicoplanin

Product ID T1733
Cas No. 61036-62-2
Purity ≥900 ug/mg, bio assay
Product Unit SizeCostQuantityStock
25 mg $66.20 In stock
100 mg $120.00 In stock
250 mg $214.00 In stock
1 g $642.10 In stock
Bulk Quote

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Description

Teicoplanin is a glycopeptide antibiotic that displays antibacterial efficacy against gram positive bacteria. Teicoplanin is an analog of vancomycin with improved lipophilicity and bioavailability when given intramuscularly. Teicoplanin inhibits peptidoglycan formation and cell wall synthesis. This compound may also cause epileptogenic activity, potentially related to downstream modulation of GABA signaling. Teicoplanin is also used as a chiral selector in capillary liquid chromatography.

Product Info

Cas No.

61036-62-2
Purity

≥900 ug/mg, bio assay
Formula

C88H95Cl2N9O33
Formula Wt.

1877.64
Chemical Name

Ristomycin A 34-O-[2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(8-methyl-1-oxononyl)amino]-.beta.-D-glucopyranosyl]-42-O-.alpha.-D-mannopyranosyl-
Solubility

Soluble in water (10 mg/mL), ethanol, methanol, DMSO, DMF.
Appearance

White to light yellow powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

T1733 MSDS PDF
Info Sheet

T1733 Info Sheet PDF

References

Nailor MD, Sobel JD. Antibiotics for gram-positive bacterial infections: vancomycin, teicoplanin, quinupristin/dalfopristin, oxazolidinones, daptomycin, dalbavancin, and telavancin. Infect Dis Clin North Am. 2009 Dec;23(4):965-82, ix. PMID: 19909893.

Takechi K, Ishikawa T, Kamei C. Epileptogenic activity induced by teicoplanin and effects of some antiepileptics in mice. J Pharmacol Sci. 2008 Aug;107(4):428-33. PMID: 18678985.

Kafková B, Bosáková Z, Tesarová E, et al. Chiral separation of beta-adrenergic antagonists, profen non-steroidal anti-inflammatory drugs and chlorophenoxypropionic acid herbicides using teicoplanin as the chiral selector in capillary liquid chromatography. J Chromatogr A. 2005 Sep 23;1088(1-2):82-93. PMID: 16130735.

Somma S, Gastaldo L, Corti A. Teicoplanin, a new antibiotic from Actinoplanes teichomyceticus nov. sp. Antimicrob Agents Chemother. 1984 Dec;26(6):917-23. PMID: 6240963.

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