LKT Labs

Biochemicals for Life Science Research

Secretin Acetate

Secretin Acetate

Product ID S1604
Cas No. 10813-74-8
Purity ≥95%
Bulk Quote

Quicklinks

Description

Secretin is an endogenous peptide hormone involved in digestion and feeding behavior; it binds to its own GPCR secretin receptor. In adipocytes, secretin stimulates lipolysis, mediated by PKA and hormone-sensitive lipase (HSL) signaling; it also induces uptake of fatty acids and secretion of MCP-1 and adiponectin. Secretin enhances ambulation distance but not exploratory activity in animal models of repetitive hyperactivity. Additionally, secretin increases expression of tyrosine hydroxylase, stimulating catecholamine secretion in PC12 neurons.

Product Info

Cas No.

10813-74-8
Purity

≥95%
Formula

C130H220N44O41
Formula Wt.

3055.41
Synonym

Secretin Acetate, porcine

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

S1604 MSDS PDF
Info Sheet

S1604 Info Sheet PDF

References

Sekar R, Chow BK. Lipolytic actions of secretin in mouse adipocytes. J Lipid Res. 2014 Feb;55(2):190-200. PMID: 24273196.

Miegueu P, Cianflone K, Richard D, et al. Effect of secretin on preadipocyte, differentiating and mature adipocyte functions. Int J Obes (Lond). 2013 Mar;37(3):366-74. PMID: 22565418.

Heinzlmann A, Kiss G, Tóth ZE, et al. Intranasal application of secretin, similarly to intracerebroventricular administration, influences the motor behavior of mice probably through specific receptors. J Mol Neurosci. 2012 Nov;48(3):558-64. PMID: 22752505.

Mahata M, Zhang K, Gayen JR, et al. Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin. Cell Tissue Res. 2011 Jul;345(1):87-102. PMID: 21597914.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A4401

    ALAL

    Tetrapeptide used as a linker in drug development.
    ≥95%
  • D3200

    Diacetoxyscirpenol

    Type A trichothecene mycotoxin produced by Fusariu...
    ≥98%
  • L1735

    Levitide

    Antimicrobial peptide found in amphibians.
    ≥95%
  • A5476

    Antagonist G

    Peptide, used for drug delivery targeting.
    ≥95%
  • C5196

    C-Myc Peptide

    Peptide, C-Myc fragment, used in protein activity ...
    ≥95%
  • G3557

    Ginsenoside Rh1

    Triterpene saponin found in species of Panax.
    ≥77%
  • P3563

    Piperlonguminine

    Found in Piper longum.
    ≥99%
  • U6801

    Urapidil

    5-HT1A agonist, α1-adrenergic antagonist.
    ≥98%
  • S0368

    Sarcophine

    Cembranoid diterpene found in Sarcophyton glaucum.
    ≥98%
  • C281006

    Chaetocin

    Chaetocin is naturally produced by Chaetomium spec...
    ≥98%
  • Q4370

    QKRPSQRSKYL

    Peptide, PKC substrate.
    ≥95%
  • X1752

    Xenin

    Endogenous peptide hormone, neurotensin analog.
    ≥95%
  • F4420

    Boc-FLFLF

    Peptide; FRP1 antagonist.
    ≥95%
  • E9417

    Exendin-4

    Peptide, GLP-1 analog found in Heloderma; GLP-1 ag...
    ≥95%
  • A5132

    Amikacin Disulfate

    Aminoglycoside; protein translation inhibitor.
    ≥98%
  • K6864

    KRQHPG

    Peptide, thyrotropin-releasing hormone progenitor ...
    ≥95%
  • B6935

    Brivudine

    Nucleoside (thymidine) analog; DNA chain terminato...
    ≥98%
  • P6264

    PPQ-102

    Pyramido-pyrrolo-quinoxalinedione; CFTR blocker.
    ≥98%
  • P3540

    PIK-75 Hydrochloride

    p110α PI3K inhibitor.
    ≥98%
  • I5753

    Ionomycin Calcium

    Polyether Ca2+ ionophore.
    ≥98%