Description
SCH-772984 is an inhibitor of ERK1/2 that exhibits anticancer chemotherapeutic activity. This compound inhibits cell and tumor growth in a variety of models, including cells featuring B-Raf, NRAS, and KRAS mutations.
SCH-772984
Product ID S0929
Cas No. 942183-80-4
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 942183-80-4 |
|---|---|
| Purity | ≥98% |
| Formula | C33H33N9O2 |
| Formula Wt. | 587.69 |
| IUPAC Name | (3R)-1-[2-oxo-2-[4-(4-pyrimidin-2-ylphenyl)piperazin-1-yl]ethyl]-N-(3-pyridin-4-yl-1H-indazol-5-yl)pyrrolidine-3-carboxamide |
| Synonym | SCH772984 |
| Solubility | DMSO 14 mg/mL warmed (23.82 mM) Water Insoluble Ethanol Insoluble |
Shipping and Storage
| Ship Temp | Ambient |
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Downloads
| MSDS | |
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| Info Sheet |
References
Nissan MH, Rosen N, Solit DB. ERK pathway inhibitors: how low should we go? Cancer Discov. 2013 Jul;3(7):719-21. PMID: 23847348.
Morris EJ, Jha S, Restaino CR, et al. Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors. Cancer Discov. 2013 Jul;3(7):742-50. PMID: 23614898.