LKT Labs

Biochemicals for Life Science Research

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Rabeprazole Sodium

Product ID R0105
Cas No. 117976-90-6
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $74.90 In stock
25 mg $149.90 In stock
100 mg $479.40 In stock
Bulk Quote

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Description

Rabeprazole is a proton pump inhibitor (PPI) that exhibits antacid activity, as it is clinically used to treat gastric ulcers and gastroesophageal reflux disease (GERD). Rabeprazole binds cysteine residues on the H+/K+ ATPase, inhibiting gastric acid secretion. Additionally, rabeprazole displays some neuroprotective potential, as it inhibits human small C-terminal domain phosphatases (Scpc), modulating expression of neuronal genes and neuronal stem cell differentiation in vitro. TEST!!!!!!

Product Info

Cas No.

117976-90-6
Purity

≥98%
Formula

C18H20N3O3S Na
Formula Wt.

381.42
Chemical Name

2[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
IUPAC Name

sodium;2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl] benzimidazol-1-ide
Synonym

Pariprazole
Melting Point

99-100°C
Solubility

Insoluble in water. Soluble in DMSO.
Appearance

Yellowish off-white crystal powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

R0105 MSDS PDF
Info Sheet

R0105 Info Sheet PDF

References

Ward RM, Kearns GL. Proton pump inhibitors in pediatrics : mechanism of action, pharmacokinetics, pharmacogenetics, and pharmacodynamics. Paediatr Drugs. 2013 Apr;15(2):119-31. PMID: 23512128.

Zhang M, Cho EJ, Burstein G, et al. Selective inactivation of a human neuronal silencing phosphatase by a small molecule inhibitor. ACS Chem Biol. 2011 May 20;6(5):511-9. PMID: 21348431.

Sanaka M, Anjiki H, Yamamoto T, et al. Rabeprazole delays gastric emptying of a nutrient liquid. J Gastroenterol Hepatol. 2007 Nov;22(11):1806-9. PMID: 17914954.

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