LKT Labs

Biochemicals for Life Science Research

Awaiting product image

Quinapril Hydrochloride

Product ID Q8134
Cas No. 82586-55-8
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $70.40 In stock
500 mg $210.30 In stock
1 g $336.30 In stock
Bulk Quote

Quicklinks

Description

Quinapril is an angiotensin II-converting enzyme (ACE) inhibitor that exhibits antihypertensive, anti-inflammatory, and cardioprotective activities; it is clinically used to treat hypertension and congestive heart failure. Quinapril decreases levels of aldosterone and increases excretion of Na+. In animal models, quinapril decreases activity of matrix metalloproteinase 2 (MMP2), suppressing left ventricular remodeling. Additionally, this compound decreases expression of pro-inflammatory cytokines in animal models of heart failure. TEST!!!!!!

Product Info

Cas No.

82586-55-8
Purity

≥98%
Formula

C25H30N2O5 • HCl
Formula Wt.

474.99
Chemical Name

(3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3- phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride
IUPAC Name

(3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl] -3,4-dihydro-1H-isoquinoline-3-carboxylic acid;hydrochloride
Synonym

Accupril, Accuprin, Accupro, Acequin, Acuitel, Korec, Quinazil
Melting Point

120-130°C
Solubility

Soluble in water (31mg/mL).
Appearance

White crystalline powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

Q8134 MSDS PDF
Info Sheet

Q8134 Info Sheet PDF

References

Brower GL, Levick SP, Janicki JS. Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H3057-64. PMID: 17308006.

We GC, Siroi MG, Qu R, et al. Effects of quinapril on myocardial function, ventricular remodeling and cardiac cytokine expression in congestive heart failure in the rat. Cardiovasc Drugs Ther. 2002 Jan;16(1):29-36. PMID: 12085975.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • I6804

    Irbesartan

    PPARγ agonist, AT1 inhibitor.

    ≥98%
  • B3373

    Bis(aziridinyl)methylamino Phosphine Sulfide

    Insect sterilizer; mutagenic.

    ≥98%
  • L9800

    LY-364947

    ALK5 (activin-like) inhibitor.

    ≥98%
  • D5897

    Doxycycline Hyclate

    Tetracycline; protein translation inhibitor, MM...

    ≥97%
  • F0150

    Famotidine

    Histamine H2 antagonist, GSK-3β inhibitor.

    ≥98%
  • L0400

    LB-100

    PP2A inhibitor.

    ≥98%
  • C291342

    CHIR-99021

    GSK3 inhibitor.

    ≥98%
  • D3374

    Disulfiram

    Aldehyde dehydrogenase, 26S proteasome, MGMT in...

    ≥98%
  • L960004

    LY-404187

    Selective positive allosteric modulator of AMPA...

    ≥98%
  • B030962

    BAY-1251152

    Inhibitor of PTEFb/CDK9.

    ≥98%
  • M3377

    Mitomycin C

    Alkaloid produced by Streptomyces, DNA cross-li...

    ≥98%
  • D1694

    Dexamethasone Acetate Monohydrate

    Steroid; glucocorticoid agonist.

    ≥98%
  • S3470

    Sirtinol

    Sirtuin inhibitor and iron chelator.

    ≥98%
  • C0121

    Caffeic Acid

    Hydroxycinnamic acid found in coffee, argan oil...

    ≥98%
  • L5749

    Lomefloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • S0831

    S-(−)-Schisandrin B

    Found in Schisandra.

    ≥98%
  • B4976

    BMS-794833

    MET, VEGFR2, Ron, Axl, FLT3 inhibitor.

    ≥98%
  • S8046

    R-Sulforaphane, High Purity

    Naturally occuring isothiocyanate found in broc...

    ≥98%
  • V1871

    Veratridine

    Binds to neurotoxin receptor site 2 on voltage-...

    ≥98%
  • G1650

    Geniposide

    Iridoid glycoside found in Gardenia.

    ≥98%