Description
PHT-427 is an inhibitor of PDK1 and Akt that exhibits anticancer chemotherapeutic activity, inhibiting tumor growth in animal models of breast cancer and non-small cell lung cancer (NSCLC).
PHT-427
Product ID P3076
Cas No. 1191951-57-1
Purity ≥98%
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Product Info
| Cas No. | 1191951-57-1 |
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| Purity | ≥98% |
| Formula | C20H31N3O2S2 |
| Formula Wt. | 409.61 |
| IUPAC Name | 4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide |
| Synonym | PHT427 |
| Solubility | DMSO 82 mg/mL (200.19 mM) Ethanol 60 mg/mL (146.48 mM) Water Insoluble |
| Appearance | White Crystal Powder |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
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| Info Sheet | |
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References
Meuillet EJ, Zuohe S, Lemos R, et al. Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor. Mol Cancer Ther. 2010 Mar;9(3):706-17. PMID: 20197390.