| Product Unit Size | Cost | Quantity | Stock |
|---|
M3814 (nedisertib) is a selective inhibitor of DNA-dependent protein kinase (DNA-PK). DNA-PK is a member of the PIKK family, overseeing DNA repair and detection of double-strand breaks. DNA-PK inhibitors such as M3814 show potential as chemosensitizing agents. TEST!!!!!!
| Cas No. | 1637542-33-6 |
|---|---|
| Purity | ≥99% |
| Formula | C24H21ClFN5O3 |
| Formula Wt. | 481.91 |
| Chemical Name | Nedisertib |
| IUPAC Name | (S)-{2-Chloro-4-fluoro-5-[7-(4-morpholinyl)-4-quinazolinyl]phenyl}(6-methoxy-3-pyridazinyl)methanol |
| Synonym | M-3814, Nedisertib, MSC2490484A |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Harnor S., Brennan A., et al. Targeting DNA-Dependent Protein Kinase for Cancer Therapy. ChemMedChem. 12(12):895-900 (2017). PMID: 28423228.