| Product Unit Size | Cost | Quantity | Stock |
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Isoindigo inhibits proliferation in various leukemia and cancer cell lines, displaying anticancer activity. Isoindigo and its derivatives may also bind the aryl hydrocarbon receptor (AhR). Additionally, similar compounds show chemotherapeutic benefits in animal models of leukemia.
| Cas No. | 476-34-6 |
|---|---|
| Purity | ≥98% |
| Formula | C16H10N2O2 |
| Formula Wt. | 262.27 |
| IUPAC Name | (3E)-3-(2-Oxo-1,2-dihydro-3H-indol-3-ylidene)-1,3-dihydro-2H-indol-2-one |
| Synonym | Isoindigotin |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Wee XK, Yang T, Go ML. Exploring the anticancer activity of functionalized isoindigos: synthesis, drug-like potential, mode of action and effect on tumor-induced xenografts. ChemMedChem. 2012 May;7(5):777-91. PMID: 22416043.
Bouchikhi F, Anizon F, Moreau P. Synthesis and antiproliferative activities of isoindigo and azaisoindigo derivatives. Eur J Med Chem. 2008 Apr;43(4):755-62. PMID: 17628214.
Nishiumi S, Yamamoto N, Kodoi R, et al. Antagonistic and agonistic effects of indigoids on the transformation of an aryl hydrocarbon receptor. Arch Biochem Biophys. 2008 Feb 15;470(2):187-99. PMID: 18086550.