LKT Labs

Biochemicals for Life Science Research

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Hypocrellin B

Product ID H9662
Cas No. 123940-54-5
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $49.70 In stock
5 mg $137.90 In stock
1 mg $49.70 In stock
10 mg $215.00 In stock
5 mg $137.90 In stock
25 mg $413.50 In stock
10 mg $215.00 In stock
100 mg $1,080.50 In stock
25 mg $413.50 In stock
100 mg $1,080.50 In stock
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Description

Hypocrellin B exhibits antibacterial, anti-metastatic, and anticancer chemotherapeutic activities. Hypocrellin B inhibits proliferation of Staphylococcus by increasing ROS levels and damaging cell walls. In ovarian cancer cells, this compound induces apoptosis and inhibits cell migration and adhesion under photodynamic stimulation; it also induces tumor regression in animal models of lymphoma. In vitro, hypocrellin B induces DNA strand breakage.

Contains ~2.5 % hypocrellin A. TEST!!!!!!

Product Info

Cas No.

123940-54-5
Purity

≥98%
Formula

C30H24O9
Formula Wt.

528.51
Solubility

Soluble in DMSO.
Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C
Ship Temp

Ambient

Downloads

MSDS

H9662 MSDS PDF
Info Sheet

H9662 Info Sheet PDF

References

Jiang Y, Leung AW, Wang X, et al. Effect of photodynamic therapy with hypocrellin B on apoptosis, adhesion, and migration of cancer cells. Int J Radiat Biol. 2014 Jul;90(7):575-9. PMID: 24661233.

Jiang Y, Leung AW, Wang X, et al. Inactivation of Staphylococcus aureus by photodynamic action of hypocrellin B. Photodiagnosis Photodyn Ther. 2013 Dec;10(4):600-6. PMID: 24284117.

Babu A, Jeyasubramanian K, Gunasekaran P, et al. Gelatin nanocarrier enables efficient delivery and phototoxicity of hypocrellin B against a mice tumour model. J Biomed Nanotechnol. 2012 Feb;8(1):43-56. PMID: 22515093.

Xu Y, Zhang Z, Zhang H. Raman spectroscopic study of DNA after photosensitive damage caused by hypocrellins A and B. Sci China C Life Sci. 1998 Aug;41(4):360-6. PMID: 18726251.

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