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Gentiopicroside

Product ID G1855
Cas No. 20831-76-9
Purity ≥97%
Product Unit SizeCostQuantityStock
10 mg $97.30 In stock
25 mg $187.30 In stock
100 mg $599.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
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Description

Gentiopicroside is a secoiridoid glycoside compound originally found in several species of Gentiana and Cephalaria plants. This compound exhibits anti-inflammatory, antioxidative, and analgesic properties. Gentiopicroside inhibits expression of NMDA receptors in the anterior cingulate cortex, which may be responsible for its ability to inhibit morphine conditioned place preference in animal models. Gentiopicroside also suppresses arachidonic acid and PMA-induced superoxide generation and, separately, caspase-mediated apoptosis, displaying hepatoprotective benefits in an animal model of liver failure. TEST!!!!!!

Product Info

Cas No.

20831-76-9

Purity

≥97%

Formula

C16H20O9

Formula Wt.

356.32

Melting Point

191°C

Appearance

Off-white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

G1855 MSDS PDF

Info Sheet

G1855 Info Sheet PDF

References

Liu SB, Ma L, Guo HJ, et al. Gentiopicroside attenuates morphine rewarding effect through downregulation of GluN2B receptors in nucleus accumbens. CNS Neurosci Ther. 2012 Aug;18(8):652-8. PMID: 22621711.

Wei S, Chen G, He W, et al. Inhibitory effects of secoiridoids from the roots of Gentiana straminea on stimulus-induced superoxide generation, phosphorylation and translocation of cytosolic compounds to plasma membrane in human neutrophils. Phytother Res. 2012 Feb;26(2):168-73. PMID: 21584870.

Lian LH, Wu YL, Wan Y, et al. Anti-apoptotic activity of gentiopicroside in D-galactosamine/ lipopolysaccharide-induced murine fulminant hepatic failure. Chem Biol Interact. 2010 Oct 6;188(1):127-33. PMID: 20558151.

Chen L, Liu JC, Zhang XN, et al. Down-regulation of NR2B receptors partially contributes to analgesic effects of Gentiopicroside in persistent inflammatory pain. Neuropharmacology. 2008 Jun;54(8):1175-81. PMID: 18410946.

Custom Order

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