Epigallocatechin Gallate Octaacetate

Name: Epigallocatechin Gallate Octaacetate
SKU: E6236
Availability: InStock

Product ID E6236

Cas No. 148707-39-5

Purity ≥98%

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Description

Peracetylated epigallocatechin-3-gallate (AcEGCG) is a close relative of epigallocatechin-3-gallate, a catechin found in green tea (Camellia sinensis). AcEGCG has a higher bioavailability than its parent compound and exhibits anti-inflammatory and anticancer chemotherapeutic activity in vitro and in vivo. AcEGCG activates ERK 1/2 signaling, inhibits acetylation of histone H3K9, and downregulates PI3K/Akt/NF-κB signaling to inhibit tumor growth in a variety of cancer-focused animal models.

Product Info

Cas No.	148707-39-5
Purity	≥98%
Formula	C₃₈H₃₄O₁₉
Formula Wt.	794.67
IUPAC Name	5,7-Diacetoxy-2-(3,4,5-triacetoxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-triacetoxybenzoate
Synonym	Peracetylated Epigallocatechin gallate, Octaacetyl Epigallocatechin gallate
Solubility	Soluble in DMSO and methanol
Appearance	White Crystal Powder

Shipping and Storage

Store Temp	4°C
Ship Temp	Ambient

Downloads

MSDS	E6236 MSDS PDF
Info Sheet	E6236 Info Sheet PDF
Brochures	Green Tea Flyer
Brochures	Natural Products Booklet

References

Chiou YS, Sang S, Cheng KH, et al. Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently prevents skin carcinogenesis by suppressing the PKD1-dependent signaling pathway in CD34+ skin stem cells and skin tumors. Carcinogenesis. 2013 Jun;34(6):1315-22. PMID: 23385063.

Chiou YS, Ma NJ, Sang S, et al. Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice. J Agric Food Chem. 2012 Apr 4;60(13):3441-51. PMID: 22409325.

Lambert JD, Sang S, Hong J, et al. Peracetylation as a means of enhancing in vitro bioactivity and bioavailability of epigallocatechin-3-gallate. Drug Metab Dispos. 2006 Dec;34(12):2111-6. PMID: 16997910.

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Epigallocatechin Gallate Octaacetate

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

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