Description
Diallyl tetrasulfide is an organosulfur that displays anticancer, antioxidative, and antimicrobial properties. In vitro, diallyl tetrasulfide increases reactive oxygen species (ROS) and heme oxygenase-1 levels and inhibits microtubule polymerization, inducing mitotic arrest. Diallyl tetrasulfide exhibits antibacterial and antifungal benefit against many microbes, including including Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), and several species of Candida and Aspergillus. Additionally, this compound decreases cadmium-mediated oxidative damage in several animal models, increasing levels of superoxide dismutase, glutathione peroxidase, and other glutathione metabolizing enzymes.