LKT Labs

Biochemicals for Life Science Research

Cytarabine

Cytarabine

Product ID C9778
Cas No. 147-94-4
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $38.30 In stock
500 mg $101.60 In stock
1 g $165.30 In stock
Bulk Quote

Quicklinks

Description

Cytarabine is a cytosine nucleoside analog that exhibits anticancer chemotherapeutic and antiviral activities. This antimetabolite is clinically used to treat chronic lymphocytic leukemia (CLL), acute lymphocytic leukemia (ALL), and non-Hodgkin lymphoma. Cytarabine inhibits RNA polymerase and DNA polymerase, preventing DNA synthesis. Although it is too toxic for antiviral use, cytarabine inhibits the growth or replication of herpesviruses such as varicella-zoster and cytomegalovirus (CMV).

Product Info

Cas No.

147-94-4
Purity

≥98%
Formula

C9H13N3O5
Formula Wt.

243.22
Chemical Name

4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone
IUPAC Name

4-amino-1-[(2R,3S,4S,5R)-3, 4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Synonym

Alexan, Arabitin, Ara-C, Cytosar, Erpalfa, Iretin, Udicil
Melting Point

212-213°C
Solubility

Soluble in water to 100 mM, DMSO to 50 mM, ethanol.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

C9778 MSDS PDF
Info Sheet

C9778 Info Sheet PDF

References

Abdel-Aziz W, Jiang HY, Hickey RJ, et al. Ara-C affects formation of cancer cell DNA synthesome replication intermediates. Cancer Chemother Pharmacol. 2000;45(4):312-9. PMID: 10755320.

Hiddemann W. Cytosine arabinoside in the treatment of acute myeloid leukemia: the role and place of high-dose regimens. Ann Hematol. 1991 Apr;62(4):119-28. PMID: 2031974.

Lauter CB, Bailey EJ, Lerner AM. Assessment of cytosine arabinoside as an antiviral agent in humans. Antimicrob Agents Chemother. 1974 Nov;6(5):598-602. PMID: 15825312.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A6264

    Apramycin Sulfate

    Aminoglycoside; protein translation inhibitor.
    ≥98%
  • H5654

    Honokiol

    Lignan found in species of Magnolia; GABA-A potent...
    ≥99%
  • S6019

    Speract

    Peptide, derived from egg outer envelope; K+ chann...
    ≥95%
  • O9234

    Oxiconazole Nitrate

    Imidazole; 14-α demethylase inhibitor.
    ≥98%
  • S9753

    Synephrine

    Endogenous alkaloid also found in citrus fruits, E...
    ≥98%
  • L8011

    D-Luciferin Sodium

    Heterocyclic light-emitting compound, natural liga...
    ≥99%
  • C5618

    Coelenterazine, natural

    Light-emitting luciferin analog found in aquatic o...
    ≥98%
  • C4418

    Clemizole Hydrochloride

    TRPC5, NS4B, histamine H1 inhibitor.
    ≥98%
  • I0800

    IC-87114

    p110δ PI3K inhibitor.
    ≥98%
  • P0244

    Palbociclib Hydrochloride

    CDK4/6 inhibitor.
    ≥99%
  • Y4800

    YM-155

    Survivin inhibitor.
    ≥99%
  • P0252

    Pancuronium Bromide

    Non-depolarizing NMJ blocker; nAChR antagonist.
    ≥98%
  • M0374

    Masitinib

    PDGFR and c-Kit inhibitor.
    ≥98%
  • D9752

    Dynasore

    Dynamin inhibitor.
    ≥98%
  • C1650

    β-Cembrenediol Methyl Ether

    Diterpene found in tobacco plants and cigarette sm...
    ≥98%
  • C0250

    Calcitonin Gene Related Peptide II, human

    Calcitonin-family peptide, involved in vasodilatio...
    ≥95%
  • E7579

    Estramustine Phosphate Disodium

    Nitrogen mustard and estradiol derivative; microtu...
    ≥95%
  • B1973

    Besifloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial DN...
    ≥98%
  • D3352

    Dinaciclib

    BRD binding agent, CDK1/2/5/9 inhibitor.
    ≥99%
  • N1868

    Neratinib

    EGFR inhibitor.
    ≥98%