Description
Cyproconazole is a triazole fungicide/pesticide with broad spectrum antifungal activity. Like many azole fungicides, cyproconazole likely inhibits 14-α demethylase, inhibiting ergosterol production and fungal cell wall synthesis. Additionally, cyproconazole may inhibit aromatase. Cyproconazole may exhibit carcinogenic activity in vivo, altering hepatic cell proliferation, serum cholesterol, and hepatic retinoic acid levels in an androgen receptor-dependent manner. Additionally, cyproconazole also acts as a nonspecific inhibitor of voltage-gated Ca2+ channels in PC12 neurons, modulating intracellular Ca2+ levels.