Description
Chalcone is an enone on which a variety of structures are based. Chalcone derivatives typically exhibit anti-inflammatory, antioxidative, neuroprotective, analgesic, anticancer, and anti-parasitic activities.
Chalcone
Product ID C2800
Cas No. 94-41-7
Purity ≥97%
| Product Unit Size | Cost | Quantity | Stock |
|---|
Product Info
| Cas No. | 94-41-7 |
|---|---|
| Purity | ≥97% |
| Formula | C15H12O |
| Formula Wt. | 208.26 |
| Chemical Name | 1,3-Diphenyl-2-propen-1-one |
| IUPAC Name | (E)-1,3-diphenylprop-2-en-1-one |
| Synonym | Chalkone, trans-Benzylideneacetophenone |
| Melting Point | 54-57°C |
| Solubility | Insoluble in water. Slightly soluble in ethanol. |
| Appearance | Light Yellow Crystal Powder |
Shipping and Storage
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
|---|---|
| Info Sheet |
References
Wu JZ, Cheng CC, Shen LL, et al. Synthetic Chalcones with Potent Antioxidant Ability on H2O2-Induced Apoptosis in PC12 Cells. Int J Mol Sci. 2014 Oct 14;15(10):18525-18539. PMID: 25318055.
Jantan I, Bukhari SN, Adekoya OA, et al. Studies of synthetic chalcone derivatives as potential inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and pro-inflammatory cytokines. Drug Des Devel Ther. 2014 Sep 16;8:1405-18. PMID: 25258510.
Abdellatif KR, Elshemy HA, Salama SA, et al. Synthesis, characterization and biological evaluation of novel 4'-fluoro-2'-hydroxy-chalcone derivatives as antioxidant, anti-inflammatory and analgesic agents. J Enzyme Inhib Med Chem. 2014 Sep 8:1-8. PMID: 25198887.
Karthikeyan C, Narayana Moorthy NS, Ramasamy S, et al. Advances in Chalcones with Anticancer Activities. Recent Pat Anticancer Drug Discov. 2014 Aug 19. [Epub ahead of print]. PMID: 25138130.
Shivahare R, Korthikunta V, Chandasana H, et al. Synthesis, structure-activity relationships, and biological studies of chromenochalcones as potential antileishmanial agents. J Med Chem. 2014 Apr 24;57(8):3342-57. PMID: 24635539.