Description
BI-2536 is a polo-like kinase 1 (PLK1) inhibitor that disrupts mitosis and cell division. BI-2536 exhibits anticancer activity and may induce apoptosis in cancer cells. TEST!!!!!!

| Product Unit Size | Cost | Quantity | Stock |
|---|
BI-2536 is a polo-like kinase 1 (PLK1) inhibitor that disrupts mitosis and cell division. BI-2536 exhibits anticancer activity and may induce apoptosis in cancer cells. TEST!!!!!!
| Cas No. | 755038-02-9 |
|---|---|
| Purity | ≥98% |
| Formula | C28H39N7O3 |
| Formula Wt. | 521.65 |
| Synonym | BI2536 |
| Solubility | Ethanol 100 mg/mL (191.69 mM) DMSO 21 mg/mL (40.25 mM) Water Insoluble |
| Appearance | Pale yellow to off-white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Colnaghi R, Wheatley SP. Liaisons between survivin and Plk1 during cell division and cell death. J Biol Chem. 2010 Jul 16;285(29):22592-604. PMID: 20427271.
Zhang J, Yang PL, Gray NS. Targeting cancer with small molecule kinase inhibitors. Nature Reviews Cancer. 2009 Jan;9:28-39.
Hydroxycinnamic acid found in various plant sou...
Inhibitor of VEGFR and FGFR.
Nucleoside (adenosine) analog; DNA chain termin...
Nitrogen mustard, DNA alkylator.
Fluorinated aminopropyl carbazole, neuroprotect...
R,R enantiomer of formoterol; β2-adrenergic an...
Calcium channel blocker.
Selective 5-HT6 receptor antagonist
Triazole; 14α demethylase inhibitor.
BRD inhibitor.
Endogenous opioid peptide; δOR and μOR agonis...
Found in Capsicum; TRPV agonist.
BK/SK, Kv1, Kv3, TASK-2 K+ channel blocker, vol...
Extract containing catechins and flavonoids fou...
Sirtuin inhibitor and iron chelator.
BH3 mimetic; Bcl-2 and Bcl-xl inhibitor.
μOR and δOR agonist, D2/D3 DA potentiator.
Antimicrobial peptide found in bee and wasp ven...
ATP competitive CDK inhibitor.