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Alyssin sulfone is a sulfone analog of sulforaphane, an isothiocyanate (ITC). Alyssin sulfone exhibits antioxidative and anticancer activity. This compound inhibits the growth of colon cancer cells in vitro and induces phase II enzymes, increasing Nrf2 activity.
| Purity | ≥97% |
|---|---|
| Formula | C7H13NO2S2 |
| Formula Wt. | 207.31 |
| IUPAC Name | 1-isothiocyanato-5-methylsulfinylpentane |
| Synonym | 5-(Methylsulfonyl)-pentyl isothiocyanate |
| Solubility | Soluble in DMSO, ethanol, chloroform. |
| Appearance | White needle-like crystals |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
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| Info Sheet |
Lubelska K, Misiewicz-Krzemińska I, Milczarek M, et al. Isothiocyanate-drug interactions in the human adenocarcinoma cell line Caco-2. Mol Cell Biochem. 2012 Aug;367(1-2):19-29. PMID: 22527941.
Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.