LKT Labs

Biochemicals for Life Science Research

Adrenocorticotropic Hormone (1-10), human

Adrenocorticotropic Hormone (1-10), human

Product ID A0963
Cas No. 2791-05-1
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $50.40 In stock
2 mg $85.10 Please Inquire
5 mg $151.20 Please Inquire
Bulk Quote

Quicklinks

Description

Adrenocorticotropic hormone (ACTH) is a peptide derived from proopiomelanocortin (POMC) processed and secreted in the pituitary gland. ACTH binds and activates melanocortin-2 (MC2) receptors, stimulating cortisol production in the adrenal cortex. ACTH exhibits anti-inflammatory and immunomodulatory activities. ACTH decreases inflammatory cytokine levels and modulates lymphocyte and macrophage functions. In vitro, ACTH stimulates proliferation of osteoblasts and increases mRNA levels of collagen I.

Product Info

Cas No.

2791-05-1
Purity

≥95%
Formula

C59H78N16O16S
Formula Wt.

1299.4
IUPAC Name

(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-(carboxymethylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(4H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
Synonym

ACTH
Solubility

Soluble in water.
Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

A0963 MSDS PDF
Info Sheet

A0963 Info Sheet PDF

References

Berkovich R, Agius MA. Mechanisms of action of ACTH in the management of relapsing forms of multiple sclerosis. Ther Adv Neurol Disord. 2014 Mar;7(2):83-96. PMID: 24587825.

Isales CM, Zaidi M, Blair HC. ACTH is a novel regulator of bone mass. Ann N Y Acad Sci. 2010 Mar;1192:110-6. PMID: 20392225.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • D3462

    Diphenhydramine Hydrochloride

    Voltage-gated Na+ channel blocker, mAChR antagonis...
    ≥98%
  • N5669

    Nordihydroguaiaretic Acid

    Phenol found in the creosote bush; 5-lipoxygenase,...
    ≥97%
  • T6934

    Trimebutine Maleate

    L-type Ca2+ channel blocker, BK K+ channel modulat...
    ≥96%
  • T0205

    3”,4”-Dehydropaclitaxel C

    Semi-synthetic taxane.
    ≥95%
  • E5222

    Endothelin-3, human

    Endogenous peptide, involved in vascular contracti...
    ≥95%
  • A6828

    N(α),N(α)-Dimethyl-L-Arginine Ammonium

    Endogenous amino acid derivative, regulates water/...
    ≥98%
  • I5215

    Indolicidin

    Antimicrobial peptide.
    ≥95%
  • P0055

    P55-TNFR Peptide

    Peptide fragment of P55 TNF receptor.
    ≥95%
  • B1996

    BEZ235

    PI3K and mTOR inhibitor.
    ≥98%
  • R0349

    Ramosetron

    5-HT3 antagonist.
    ≥98%
  • H1646

    Helospectin II

    Peptide originally found in Heloderma.
    ≥95%
  • C5654

    Concanavalin A

    Lectin found in Canavelia, plant mitogen that bind...
    ≥98%
  • I7155

    Isoindigo

    Potential AhR binding agent.
    ≥98%
  • I0902

    Icaritin

    Flavonoid found in Epimedium.
    ≥98%
  • C6982

    Crustacean Cardioactive Peptide

    Neuropeptide hormone found in arthropods.
    ≥95%
  • M7530

    [Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone

    Semi-synthetic peptide, melanocortin analog; MCR a...
    ≥98%
  • B5044

    BML-277

    Arylbenzimidazole; CHK2 inhibitor.
    ≥98%
  • M5877

    Motesanib Diphosphate

    VEGFR, PDGFR, c-Kit, RET inhibitor.
    ≥98%
  • T0091

    7-(Triethylsilyl)-10-deacetylbaccatin III

    Taxol derivative.
    ≥97%
  • K5606

    Kobe 2602

    Ras inhibitor.
    ≥98%