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7,10-DiTroc-10-Deacetyl Baccatin III

7,10-DiTroc-10-Deacetyl Baccatin III

Product ID B004086
Cas No. 95603-44-4
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $108.00 Please Inquire
5 mg $308.70 Please Inquire
10 mg $551.30 Please Inquire
25 mg $882.00 Please Inquire
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  • Product Info
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  • Description
  • Product Info
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Description

7,10-DiTroc-10-Deacetyl Baccatin III is an intermediate in the synthesis of a metabolite of Docetaxel, an antineoplastic.

Product Info

Cas No.

95603-44-4

Purity

≥95%

Formula

C35H38Cl6O14

Formula Wt.

895.38

Chemical Name

7,10-bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetyl baccatin III

Synonym

7,10-Bis(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III,7,10-Bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III,7,10-Di(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin III,7,10-Di-O-[(2,2,2-trichloroethoxy)carbonyl]baccatin III,Carbonic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-9,11-dihydroxy-4a,8,13,13-tetraMethyl-5-oxo-7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-4,6-diyl bis(2,2,2-trichloroethyl) Ester,7,10-Troc-10-DAB,0-Troc-10-DAB

Melting Point

232-234℃

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

B004086 Info Sheet PDF

References

Lu HF1, Sun X, Xu L, Lou LG, Lin GQ Design, synthesis and biological evaluation of novel fluorinated docetaxel analogues. Eur J Med Chem. 2009 44(2):482-91. PMID: 18524425 DOI: 10.1016/j.ejmech.2008.04.004

Iwao Ojima,Ivan Habus. Mangzhu Zhao, et.al New and efficient approaches to the semisynthesis of taxol and its C-13 side chain analogs by means of β-lactam synthon method Tetrahedron 48, 6985-7012, 1992. doi.org/10.1016/S0040-4020(01)91210-4

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