| Product Unit Size | Cost | Quantity | Stock |
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4-Bromoflavone displays antioxidative and chemopreventive activities. 4-Bromoflavone activates Nrf2-Keap1-ARE complex signaling and also induces quinone reductase and other phase II enzymes. Additionally, this compound prevents the development of mammary tumors, increasing tumor latency in vivo.
| Cas No. | 1218-80-0 |
|---|---|
| Purity | ≥98% |
| Formula | C15H9BrO2 |
| Formula Wt. | 301.13 |
| IUPAC Name | 6-bromo-2-phenylchromen-4-one |
| Synonym | 6-Bromo-2-phenylbenzopyran, 6-Bromo-2-pheynyl- 4H-1-benzopyran-4-one, 6-Bromoflavone |
| Melting Point | 176-178°C (lit.) |
| Appearance | Off-White crystalline powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Lee JS, Surh YJ. Nrf2 as a novel molecular target for chemoprevention. Cancer Lett. 2005 Jun 28;224(2):171-84. PMID: 15914268.
Mehta RG, Pezzuto JM. Discovery of cancer preventive agents from natural products: from plants to prevention. Curr Oncol Rep. 2002 Nov;4(6):478-86. PMID: 12354359.
Song LL, Kosmeder JW 2nd, Lee SK, et al. Cancer chemopreventive activity mediated by 4'-bromoflavone, a potent inducer of phase II detoxification enzymes. Cancer Res. 1999 Feb 1;59(3):578-85. PMID: 9973203.