Description
Alloxan is an oxygenated pyrimidine and toxic analog of glucose. Alloxan destroys β cells and is used in research models to induce diabetes. This compound does not affect human cells.
Alloxan Monohydrate
Product ID A4547
Cas No. 2244-11-3
Purity ≥98%
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Product Info
| Cas No. | 2244-11-3 |
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| Purity | ≥98% |
| Formula | C4H2N2O4 • H2O |
| Formula Wt. | 160.08 |
| Chemical Name | 2,4,5,6(1H,3H)-pyrimidinetetrone monohydrate |
| IUPAC Name | 5,5-dihydroxy-1,3-diazinane-2,4,6-trione |
| Synonym | Alloxan |
| Melting Point | 255°C |
| Solubility | Soluble in water. |
| Appearance | Tan Powder |
Shipping and Storage
| Store Temp | 4°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Franzén S, Friederich-Persson M, Fasching A, et al. Differences in susceptibility to develop parameters of diabetic nephropathy in four mouse strains with type 1 diabetes. Am J Physiol Renal Physiol. 2014 May 15;306(10):F1171-8. PMID: 24623147.
Tyrberg B, Andersson A, Borg LA. Species differences in susceptibility of transplanted and cultured pancreatic islets to the beta-cell toxin alloxan. Gen Comp Endocrinol. 2001 Jun;122(3):238-51. PMID: 11356036.
Eizirik DL, Pipeleers DG, Ling Z, et al. Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9253-6. PMID: 7937750.