• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Awaiting product image

Tobramycin Sulfate

Product ID T5605
Cas No. 79645-27-5
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $57.60 In stock
500 mg $198.50 In stock
1 g $275.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Tobramycin is an aminoglycoside antibiotic that exhibits antibacterial and anti-inflammatory activities. Tobramycin prevents formation of the 70S bacterial ribosomal complex, inhibiting protein translation; it is highly effective in the treatment of Pseudomonas infections. In vitro, tobramycin inhibits T cell and neutrophil migration. In separate cellular models, this compound also decreases activation of NF-κB, expression of MUC5AC, and phosphorylation of ERK and p38 MAPK. TEST!!!!!!

Product Info

Cas No.

79645-27-5

Purity

≥98%

Formula

(C18H37N5O9)2 • 5H2SO4

Formula Wt.

1425.45

Chemical Name

O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1->6)-O- [2,6-diamino-2,3,6-trideoxy-α-D-ribo-hexopyranosyl- (1->4)]-2-deoxy-D-streptamine sulfate

IUPAC Name

4-amino-2-[4, 6-diamino-3-[3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2- hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol;sulfuric acid

Synonym

Gernebcin, Nebcin, Nebicina, Tobra, Tobradistin

Melting Point

287°C(dec.)

Solubility

Soluble in water (50 mg/mL).

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T5605 MSDS PDF

Info Sheet

T5605 Info Sheet PDF

References

Papich MG. Antibiotic treatment of resistant infections in small animals. Vet Clin North Am Small Anim Pract. 2013 Sep;43(5):1091-107. PMID: 23890241.

Gziut M, MacGregor HJ, Nevell TG, et al. Anti-inflammatory effects of tobramycin and a copper-tobramycin complex with superoxide dismutase-like activity. Br J Pharmacol. 2013 Mar;168(5):1165-81. PMID: 23072509.

Nakamura S, Yanagihara K, Araki N, et al. High-dose tobramycin inhibits lipopolysaccharide-induced MUC5AC production in human lung epithelial cells. Eur J Pharmacol. 2011 Mar 21. [Epub ahead of print]. PMID: 21414310.

Periti P. Tobramycin--clinical pharmacology and chemotherapy. J Chemother. 1996 Jan;8 Suppl 1:3-30. PMID: 8948764.

King P, Citron DM, Griffith DC, et al. Effect of oxygen limitation on the in vitro activity of levofloxacin and other antibiotics administered by the aerosol route against Pseudomonas aeruginosa from cystic fibrosis patients. Diagn Microbiol Infect Dis. 2010 Feb;66(2):181-186. PMID: 19828274.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P6858

    Procarbazine Hydrochloride

    Hydrazine derivative, DNA alkylator; MAO inhibi...

    ≥97%
  • B3280

    Bis(salicyl) Fumarate

    Aspirin analog; hemoglobin chain cross-linker.<...

    ≥98%
  • P7056

    Procaterol Hydrochloride

    β2-adrenergic agonist.

    ≥98%
  • A761001

    AT-7519 free base

    ATP competitive CDK inhibitor.

    ≥98%
  • T0116

    2″,3″-Dihydrocephalomannine

    Cephalomannine derivative found in Taxus; poten...

    ≥90%
  • D3202

    Diallyl Trisulfide

    Organosulfur found in garlic.

    ≥98%
  • P2303

    Phallacidin

    Phallotoxin found in Amanita phalloides; microt...

    ≥98%
  • O0977

    Octopamine Hydrochloride

    Endogenous biogenic amine, norepinephrine-like ...

    ≥98%
  • B4248

    BKM120

    PI3K inhibitor, microtubule polymerization inhi...

    ≥98%
  • R3584

    Rivaroxaban

    Oxazolidone derivative; Factor Xa inhibitor.

    ≥98%
  • P8370

    Purmorphamine

    Hedgehog and Smo agonist.

    ≥98%
  • B349921

    BIX-01294

    Specific inhibitor of histone methyltransferase...

    ≥99%
  • M3584

    Mivacurium

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%
  • P2304

    Phalloidin

    Phallotoxin found in Amanita phalloides; microt...

    ≥95%
  • B242042

    BGB-283

    Dual RAF/EGFR inhibitor.

    ≥98%
  • F7657

    Ftorafur

    5-fluorouracil prodrug, pyrimidine analog; thym...

    ≥98%
  • P0932

    PCI-32765

    BTK and IL-2-inducible kinase inhibitor.

    ≥99%
  • D1695

    Dexamethasone Phosphate Sodium

    Steroid; glucocorticoid agonist.

    ≥97%
  • B3200

    BI-2536

    PLK1 inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only