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Naproxen is a propionic non-steroidal anti-inflammatory drug (NSAID) that exhibits antipyretic, analgesic, anti-inflammatory, and antiviral activities. Naproxen inhibits COX-1 and COX-2 and is clinically used to treat fever, swelling, and pain. In vitro, naproxen inhibits influenza virus infection through binding of the nucleoprotein and preventing initiation of transcription and replication.
| Cas No. | 22204-53-1 |
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| Purity | ≥98% |
| Formula | C14H14O3 |
| Formula Wt. | 230.26 |
| Chemical Name | S(+)6-Methoxy-α methyl-2-naphthaleneacetic acid |
| IUPAC Name | (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid |
| Synonym | S-Naproxen, Nonyl, Equiproxen, Napren, Pranoxen |
| Melting Point | 155-158°C |
| Solubility | Soluble in ethanol and acetone. Insoluble in water. |
| Appearance | White or Almost White Crystalline Powder |
| Store Temp | 4°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Lejal N, Tarus B, Bouguyon E, et al. Structure-based discovery of the novel antiviral properties of naproxen against the nucleoprotein of influenza A virus. Antimicrob Agents Chemother. 2013 May;57(5):2231-42. PMID: 23459490.
Duggan KC, Walters MJ, Musee J, et al. Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen. J Biol Chem. 2010 Nov 5;285(45):34950-9. PMID: 20810665.