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Epigallocatechin Gallate Octaacetate

Epigallocatechin Gallate Octaacetate

Product ID E6236
Cas No. 148707-39-5
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $57.00 In stock
25 mg $90.00 In stock
100 mg $269.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Peracetylated epigallocatechin-3-gallate (AcEGCG) is a close relative of epigallocatechin-3-gallate, a catechin found in green tea (Camellia sinensis). AcEGCG has a higher bioavailability than its parent compound and exhibits anti-inflammatory and anticancer chemotherapeutic activity in vitro and in vivo. AcEGCG activates ERK 1/2 signaling, inhibits acetylation of histone H3K9, and downregulates PI3K/Akt/NF-κB signaling to inhibit tumor growth in a variety of cancer-focused animal models.

Product Info

Cas No.

148707-39-5

Purity

≥98%

Formula

C38H34O19

Formula Wt.

794.67

IUPAC Name

5,7-Diacetoxy-2-(3,4,5-triacetoxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-triacetoxybenzoate

Synonym

Peracetylated Epigallocatechin gallate, Octaacetyl Epigallocatechin gallate

Solubility

Soluble in DMSO and methanol

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

E6236 MSDS PDF

Info Sheet

E6236 Info Sheet PDF

Brochures

Green Tea Flyer

Brochures

Natural Products Booklet

References

Chiou YS, Sang S, Cheng KH, et al. Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently prevents skin carcinogenesis by suppressing the PKD1-dependent signaling pathway in CD34+ skin stem cells and skin tumors. Carcinogenesis. 2013 Jun;34(6):1315-22. PMID: 23385063.

Chiou YS, Ma NJ, Sang S, et al. Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice. J Agric Food Chem. 2012 Apr 4;60(13):3441-51. PMID: 22409325.

Lambert JD, Sang S, Hong J, et al. Peracetylation as a means of enhancing in vitro bioactivity and bioavailability of epigallocatechin-3-gallate. Drug Metab Dispos. 2006 Dec;34(12):2111-6. PMID: 16997910.

Custom Order

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