LKT Labs

Biochemicals for Life Science Research

Awaiting product image

Rivaroxaban

Product ID R3584
Cas No. 366789-02-8
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $107.20 In stock
5 mg $370.90 In stock
25 mg $1,318.40 In stock
Bulk Quote

Quicklinks

Description

Rivaroxaban is an orally bioavailable oxazolidone derivative that acts as an antithrombotic/anticoagulant, reversibly inhibiting factor Xa. Rivaroxaban directly binds to the S1 and S4 pockets of factor Xa and inhibits both free and clot-bound forms. In vitro models indicate that rivaroxaban may also exert inhibitory effects during the early stages of bone formation, as it inhibits hormone-stimulated modulation of ER and 1-OHase expression as well as DNA synthesis, creatine kinase activity, and alkaline phosphatase activity. TEST!!!!!!

Product Info

Cas No.

366789-02-8
Purity

≥98%
Formula

C19H18ClN3O5S
Formula Wt.

435.88
IUPAC Name

5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1, 3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide
Solubility

MeOH
Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

R3584 MSDS PDF
Info Sheet

R3584 Info Sheet PDF

References

Kreutz R. Pharmacokinetics and Pharmacodynamics of Rivaroxaban - An Oral, Direct Factor Xa Inhibitor. Curr Clin Pharmacol. 2013 Nov 11. [Epub ahead of print]. PMID: 24218999.

Somjen D, Katzburg S, Gigi R, et al. Rivaroxaban, a direct inhibitor of the coagulation factor Xa interferes with hormonal-induced physiological modulations in human female osteoblastic cell line SaSO2. J Steroid Biochem Mol Biol. 2013 May;135:67-70. PMID: 23333933

Gigi R, Salai M, Dolkart O, et al. The effects of direct factor Xa inhibitor (Rivaroxaban) on the human osteoblastic cell line SaOS2. Connect Tissue Res. 2012;53(6):446-50. PMID: 22800431.

Samama MM. The mechanism of action of rivaroxaban--an oral, direct Factor Xa inhibitor--compared with other anticoagulants. Thromb Res. 2011 Jun;127(6):497-504. PMID: 20888031.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • M964098

    Mycophenolate Mofetil

    Prodrug of the compound mycophenolic acid.

    ≥98%
  • C0344

    Calphostin C

    Found in Cladosporium; PKC inhibitor.

    ≥95%
  • P577520

    Ponatinib

    pan-Bcr-Abl tyrosine kinase inhibitor.

    ≥99%
  • L5873

    Losartan Potassium

    AT1 antagonist.

    ≥98%
  • A4443

    L-(+)-Alliin

    Optically active cysteine derivative found in A...

    ≥98%
  • G346851

    Givinostat Hydrochloride

    Non-selective HDAC inhibitor.

    ≥98%
  • E6432

    (−)-Epinephrine

    Active isomer of epinephrine, endogenous hormon...

    ≥98%
  • M0124

    Magainin 1

    Antimicrobial peptide found in frogs, induces p...

    ≥95%
  • N3310

    Nicotinamide

    Amide form of vitamin B3 required for productio...

    ≥98%
  • Y1000

    Y27632 Dihydrochloride

    ROCK inhibitor.

    ≥99%
  • E5241

    Met-Enkephalin

    Endogenous opioid peptide; δOR and μOR agonis...

    ≥95%
  • H9861

    Hypericin

    Naphthodianthrone found in Hypericum; dopamine ...

    ≥98%
  • T5769

    Toremifene Base

    SERM, androgen modulator.

    ≥98%
  • F4581

    5-Fluorocytosine

    Synthetic antifungal.

    ≥98%
  • H1862

    Heptaplatin

    Pt-based DNA cross-linker.

    ≥98%
  • C4557

    Clofibrate

    Fibrate; PPARα agonist.

    ≥98%
  • L960008

    LY-3177833

    Cdc7 inhibitor.

    ≥99%
  • F5773

    Fosinopril Sodium

    ACE inhibitor.

    ≥98%
  • I6068

    Ipriflavone

    Synthetic isoflavone.

    ≥98%
  • E583731

    Eosin Y Disodium

    A tetrabromofluorescein yellow-red dye from the...

    ≥97%