LKT Labs

Biochemicals for Life Science Research

Terlipressin Acetate

Terlipressin Acetate

Product ID T1673
Cas No. 14636-12-5
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $98.50 In stock
5 mg $344.50 In stock
Bulk Quote

Quicklinks

Description

Terlipressin is a synthetic peptide agonist at vasopressin 1 receptors (AVPR1) and is clinically used to treat portal hypertension by decreasing portal pressure; it is an analog of vasopressin. Terlipressin is a vasopressin analog that exhibits both vasoconstrictive and antihypertensive activities in various models. Terlipressin induces gastroparesis in vivo, increasing slow wave frequency in stomach and intestines. Terlipressin may also improve renal function in subjects with hepatorenal syndrome.

Product Info

Cas No.

14636-12-5
Purity

≥95%
Formula

C52H74N16O15S2
Formula Wt.

1227.37
IUPAC Name

(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
Synonym

Glypressin, Lucassin, Terlipressinum
Solubility

Insoluble in water. Soluble in DMSO.
Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

T1673 MSDS PDF
Info Sheet

T1673 Info Sheet PDF

References

Lange M, Van Aken H, Westphal M, et al. Role of vasopressinergic V1 receptor agonists in the treatment of perioperative catecholamine-refractory arterial hypotension. Best Pract Res Clin Anaesthesiol. 2008 Jun;22(2):369-81. PMID: 18683482.

Betrosian AP, Agarwal B, Douzinas EE. Acute renal dysfunction in liver diseases. World J Gastroenterol. 2007 Nov 14;13(42):5552-9. PMID: 17948928.

Nowak L, Królczyk G, Sobocki J, et al. Gastric stimulation is effective in reversing vasopressin induced gastroparesis. Folia Med Cracov. 2004;45(1-2):71-9. PMID: 16276827.

Heinemann A, Stauber RE. Effect of terlipressin on in vitro vascular hyporeactivity of portal hypertensive rats. J Hepatol. 1996 Jun;24(6):739-46. PMID: 8835750.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C9711

    Cyclovirobuxine D

    Found in Buxus; hERG K+ channel inhibitor.
    ≥97%
  • E9416

    Exendin-3

    Peptide, GLP-1 analog found in Heloderma; GLP-1 ag...
    ≥95%
  • S5752

    Somatostatin-28 (1-12)

    Endogenous neuropeptide hormone; somatostatin agon...
    ≥95%
  • L0251

    Laminin Peptide CDPGYIGSR

    Laminin-derived nonapeptide.
    ≥98%
  • G7342

    GSK-2126458

    p110α PI3K and mTOR inhibitor.
    ≥99%
  • P0268

    Parasin I

    Histone H2-derived antimicrobial peptide found in ...
    ≥95%
  • A0101

    4-bromo-A23187

    Non-fluorescent halogenated A23187 analog, Ca2+ io...
    ≥98%
  • F5872

    N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys

    Peptide, involved in neutrophil activation; FPR1 a...
    ≥95%
  • A7618

    Atenolol

    β1-adrenergic antagonist.
    ≥98%
  • N5986

    Novobiocin Sodium

    Aminocoumarin; bacterial DNA gyrase inhibitor.
    ≥98%
  • P0007

    Pituitary Adenylate Cyclase-activating Polypeptide (6-27), human, sheep, rat

    Endogenous peptide, involved in paracrine and auto...
    ≥95%
  • P7057

    Protodioscin

    Saponin found in Dioscorea; Na+/K+ ATPase and Ca2+...
    ≥98%
  • G3355

    Ginkgolide B

    Terpene lactone found in Ginkgo; GlyR antagonist.
    ≥95%
  • L2876

    Luteinizing Hormone Releasing Hormone III, lamprey

    Peptide hormone found in eels; GnRH agonist, weak ...
    ≥98%
  • A2401

    AG-18

    EGFR and PDGFR inhibitor
    ≥98%
  • N0163

    2-(1,8-Naphthyridin-2-yl)phenol

    Naphthalene; indirect STAT1 agonist.
    ≥98%
  • S3586

    SIVmac239-2

    Peptide, SIV fragment.
    ≥95%
  • E0073

    Ebselen

    Synthetic glutathione peroxidase mimetic; yeast sp...
    ≥98%
  • B1996

    BEZ235

    PI3K and mTOR inhibitor.
    ≥98%
  • AS113

    Evodia Standards Kit

    Evodia Standards Kit Contents: -Column: Cosmosil 2...