LKT Labs

Biochemicals for Life Science Research

Secretin, rat

Secretin, rat

Product ID S1607
Cas No. 121028-49-7
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $141.60 In stock
1 mg $239.40 In stock
2.5 mg $422.00 In stock
Bulk Quote

Quicklinks

Description

Secretin is an endogenous peptide hormone involved in digestion and feeding behavior; it binds to its own GPCR secretin receptor. In adipocytes, secretin stimulates lipolysis, mediated by PKA and hormone-sensitive lipase (HSL) signaling; it also induces uptake of fatty acids and secretion of MCP-1 and adiponectin. Secretin enhances ambulation distance but not exploratory activity in animal models of repetitive hyperactivity. Additionally, secretin increases expression of tyrosine hydroxylase, stimulating catecholamine secretion in PC12 neurons.

Product Info

Cas No.

121028-49-7
Purity

≥95%
Formula

C129H216N42O42
Formula Wt.

3027.42
Solubility

Soluble in water (2 mg/mL).
Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

S1607 MSDS PDF
Info Sheet

S1607 Info Sheet PDF

References

Sekar R, Chow BK. Lipolytic actions of secretin in mouse adipocytes. J Lipid Res. 2014 Feb;55(2):190-200. PMID: 24273196.

Miegueu P, Cianflone K, Richard D, et al. Effect of secretin on preadipocyte, differentiating and mature adipocyte functions. Int J Obes (Lond). 2013 Mar;37(3):366-74. PMID: 22565418.

Heinzlmann A, Kiss G, Tóth ZE, et al. Intranasal application of secretin, similarly to intracerebroventricular administration, influences the motor behavior of mice probably through specific receptors. J Mol Neurosci. 2012 Nov;48(3):558-64. PMID: 22752505.

Mahata M, Zhang K, Gayen JR, et al. Catecholamine biosynthesis and secretion: physiological and pharmacological effects of secretin. Cell Tissue Res. 2011 Jul;345(1):87-102. PMID: 21597914.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A5035

    5-Aminosalicylic Acid

    Salicylic acid derivative; PPARγ agonist, potenti...
    ≥98%
  • C5260

    C-type Natriuretic Peptide (1-22), pig/human/rat

    Endogenous cardiomodulatory peptide; NPR-B agonist...
    ≥95%
  • T0107

    Xylosyltaxol C

    Taxane found in species of Taxus; potential microt...
    ≥90%
  • D0169

    Darifenacin Hydrobromide

    M3 mAChR antagonist.
    ≥98%
  • F3206

    Fibrinolysis Inhibiting Factor

    Peptide; fibrinolysis inhibitor.
    ≥98%
  • H0169

    Harringtonine

    Cephalotaxine alkaloid originally found in Cephalo...
    ≥97%
  • C0273

    Casin

    Cdc42 GTPase inhibitor.
    ≥97%
  • D5746

    Dolasetron

    5-HT3 antagonist.
    ≥98%
  • N1994

    Neurotensin, frog

    Endogenous neuropeptide involved in hormone releas...
    ≥95%
  • A5032

    D,L-Aminoglutethimide

    Aromatase inhibitor.
    ≥98%
  • Z161022

    α-Zearalanol

    α-Zearalanol is a mycotoxin that has structural s...
    ≥98%
  • D0353

    Danofloxacin Mesylate

    Fluoroquinolone; bacterial DNA gyrase inhibitor.
    ≥98%
  • G1849

    Gemifloxacin Mesylate

    Fluoroquinolone; bacterial DNA gyrase inhibitor.
    ≥98%
  • R0349

    Ramosetron

    5-HT3 antagonist.
    ≥98%
  • G4481

    Glucagon-like Peptide I Amide (7-36), human

    Endogenous peptide hormone, GLP-1 fragment, involv...
    ≥95%
  • A6970

    Artemether

    Sesquiterpene lactone derived from Artemesia.
    ≥98%
  • R0253

    Ranitidine Hydrochloride

    Histamine H2 inverse agonist.
    ≥98%
  • A3080

    AHU-377 Tris Salt

    LBQ657 prodrug; neprilysin inhibitor.
    ≥99%
  • D3372

    Disodium Cycloheptylaminomethylene Diphosphate

    Bisphosphonate; squalene synthase inhibitor.
    ≥98%
  • I4962

    Isoimperatorin

    Furocoumarin; COX-2 inhibitor.
    ≥98%