LKT Labs

Biochemicals for Life Science Research

Pituitary Adenylate Cyclase-activating Polypeptide (1-38), human, sheep, rat

Pituitary Adenylate Cyclase-activating Polypeptide (1-38), human, sheep, rat

Product ID P0006
Cas No. 124123-15-5
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $390.70 In stock
1 mg $664.70 In stock
2.5 mg $1,172.00 In stock
Bulk Quote

Quicklinks

Description

Pituitary adenylate cyclase-activating polypeptide (PACAP) is an endogenous peptide that stimulates cAMP production in the anterior pituitary. PACAP and PACAP-related peptide (PRP) regulate immune function and display increases in expression when hosts are challenged with bacterial pathogens. PACAP and PRP also control expression of reproductive hormones such as follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Additionally, PACAP and PRP bind the PAC1 receptor and VPAC1/2 receptors. PACAP itself inhibits K+ amplitude of delayed rectifier K+ channels, exhibiting anti-apoptotic activity in cerebellar granule cells.

Product Info

Cas No.

124123-15-5
Purity

≥95%
Formula

C203H331N63O53S
Formula Wt.

4534.36
Synonym

PACAP (1-38)
Solubility

Soluble in water.
Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

P0006 MSDS PDF
Info Sheet

P0006 Info Sheet PDF

References

Nam BH, Moon JY, Kim YO, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013 Jan;164(1):18-28. PMID: 23026070.

Tam JK, Lee LT, Cheng CH, et al. Discovery of a new reproductive hormone in teleosts: pituitary adenylate cyclase-activating polypeptide-related peptide (PRP). Gen Comp Endocrinol. 2011 Sep 15;173(3):405-10. PMID: 21703272.

Vaudry D, Falluel-Morel A, Bourgault S, et al. Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev. 2009 Sep;61(3):283-357. PMID: 19805477.

Mei YA, Vaudry D, Basille M, et al. PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. Eur J Neurosci. 2004 Mar;19(6):1446-58. PMID: 15066141.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E4668

    ELR-510444

    Microtubule polymerization inhibitor.
    ≥98%
  • T2800

    Thalidomide

    Immunomodulator; teratogen.
    ≥98%
  • L5658

    Lonidamine

    Hexokinase inhibitor, aerobic glycolysis inhibitor...
    ≥98%
  • V3345

    Vildagliptin

    DPP4 inhibitor.
    ≥97%
  • P6957

    Protopanaxadiol

    Triterpene sapogenin found in species of Panax; GA...
    ≥98%
  • P0001

    P1 Peptide

    Octapeptide, prevents EGFR-PLCγ association.
    ≥95%
  • B8112

    Budesonide

    Steroid; glucocorticoid agonist.
    ≥97%
  • T3094

    Thymopentin Acetate

    Peptide fragment of thymopoietin, immunostimulant.
    ≥95%
  • V3278

    Vitamin E Acetate

    Vitamin E, antioxidant.
    ≥98%
  • A9817

    Azelaic Acid

    Dicarboxylic acid found in Arabidopsis; PPARγ ago...
    ≥98%
  • R0272

    Rasagiline Mesylate

    MAO-A/B inhibitor.
    ≥98%
  • AS104

    Camptothecins Standards Kit

    Camptothecins Standards Kit Contents: -Column: Cos...
  • C4535

    Clinafloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial DN...
    ≥98%
  • B7118

    Brevetoxin 3 42-carboxylic Acid

    Brevetoxins are lipid-soluble polyether neurotoxin...
    ≥95%
  • L0226

    Lagochiline

    Diterpene alkaloid found in Lagochilus.
    ≥98%
  • T5611

    δ-Tocotrienol

    Antioxidant, vitamin E derivative found in vegetab...
    ≥98%
  • S0170

    Sarafloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial DN...
    ≥91%
  • Z7477

    ZSTK474

    PI3K inhibitor.
    ≥98%
  • P1853

    Penicillin V Potassium

    Hydrophobic β-lactam; penicillin binding protein ...
    ≥98%
  • D5747

    Dolasetron Mesylate Hydrate

    5-HT3 antagonist.
    ≥98%