| Product Unit Size | Cost | Quantity | Stock |
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Tyr-MIF-1 is a neuromodulatory tetrapeptide of the MIF-1 family that acts as an antagonist at μ-opioid receptors (μORs), inhibits opioid-induced antinociception and analgesia in vivo. When administered alone, Tyr-MIF-1 may exhibit histamine-dependent antinociceptive activity itself. Additionally, Tyr-MIF-1 increases gastric motility, stimulating antral and duodenal myoelectric activity. TEST!!!!!!
| Cas No. | 77133-61-0 |
|---|---|
| Purity | ≥95% |
| Formula | C22H33N5O5 |
| Formula Wt. | 447.54 |
| Synonym | (Tyr0)-Melanocyte-stimulating hormone-release inhibiting factor, MIF-1 |
| Solubility | Soluble in water. |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
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Pan W, Kastin AJ. From MIF-1 to endomorphin: the Tyr-MIF-1 family of peptides. Peptides. 2007 Dec;28(12):2411-34. PMID: 17988762.
Bocheva A, Dzambazova-Maximova E. Antiopioid properties of the TYR-MIF-1 family. Methods Find Exp Clin Pharmacol. 2004 Nov;26(9):673-7. PMID: 15632952.
Zamfirova R, Bocheva A, Todorov S. Involvement of H2-receptors in the mechanism of analgesic action of Tyr-MIF-1. Arch Physiol Biochem. 2003 Dec;111(5):443-7. PMID: 16026032.
Million M, Fioramonti J, Bueno L. Central administration of Tyr-MIF-1 stimulates gastrointestinal motility in rats: evidence for the involvement of dopamine, sigma and CCK receptors. Neuropeptides. 1994 Feb;26(2):77-85. PMID: 7909585.