LKT Labs

Biochemicals for Life Science Research

[Hyp3]-Bradykinin

[Hyp3]-Bradykinin

Product ID B6810
Cas No. 37642-65-2
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $75.70 Please Inquire
1 mg $129.30 Please Inquire
2.5 mg $226.90 Please Inquire
Bulk Quote

Quicklinks

Description

Bradykinin is a peptide that exhibits natriuretic, antioxidative, vasodilatory, and pro-angiogenic activities. Bradykinin stimulates bradykinin receptors and increases PLC activity, decreasing ENaC open probability, inhibiting distal nephron Na+ transport, and inducing natriuresis. In vitro, bradykinin decreases H2O2-induced senescence, increases activity of superoxide dismutase (SOD), and suppresses DNA damage, ROS production, and NADPH oxidase activity. Additionally, bradykinin increases expression of VEGF and promotes tube formation in prostate cancer cells.

Product Info

Cas No.

37642-65-2
Purity

≥95%
Formula

C50H73N15O12
Formula Wt.

1076.23
Solubility

Soluble in water, acid.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

B6810 MSDS PDF
Info Sheet

B6810 Info Sheet PDF

References

Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C9779

    Cytisine

    Alkaloid found in Fabaceae family plants; α3β4 n...
    ≥98%
  • S7717

    Sterigmatocystin

    Mycotoxin produced by Aspergillus; carcinogen.
    ≥98%
  • D8145

    Duloxetine Hydrochloride

    SERT and NET inhibitor, Nav1.7 Na+ channel blocker...
    ≥99%
  • A5302

    Anastrozole

    Aromatase inhibitor.
    ≥99%
  • B004084

    7,10,13-Trimethyl-10-Deacetyl Baccatin III

    7,10,13-Trimethyl-10-Deacetyl Baccatin III or 10-D...
    ≥95%
  • P0218

    Paeoniflorin

    Found in Paeonia; L-type Ca2+ channel blocker.
    ≥98%
  • S3343

    Silybin

    Flavonoid originally found in Silybum (milk thistl...
    ≥97%
  • U6956

    Uroguanylin, human

    Endogenous peptide, involved in water/Na+ homeosta...
    ≥95%
  • S0049

    Salmon Calcitonin Acetate

    Peptide, involved in feeding behavior and insulin ...
    ≥95%
  • A9662

    AZ-628

    B-Raf and c-Raf inhibitor.
    ≥96%
  • P2858

    4-α-Phorbol-12-myristate-13-acetate

    Negative control for PKC activation.
    ≥98%
  • G0175

    Gastric Inhibitory Peptide, human

    Endogenous peptide hormone, somatostatin analog; G...
    ≥95%
  • T5871

    Torin 2

    Tricyclic benzonaphthyridinone; mTORC1/2 inhibitor...
    ≥98%
  • T1018

    sec-Butyl Analog of Paclitaxel

    sec-Butyl Analog of Paclitaxel is an impurity that...
    ≥95%
  • S3033

    Shikimic Acid

    Cyclohexanecarboxylic acid found in various plants...
    ≥98%
  • P7057

    Protodioscin

    Saponin found in Dioscorea; Na+/K+ ATPase and Ca2+...
    ≥98%
  • S0459

    SB-590885

    B-Raf inhibitor.
    ≥97%
  • S4932

    SMI-4a

    Thiazolidine; Pim kinase inhibitor.
    ≥99%
  • S1810

    Secnidazole

    Nitroimidazole, binds DNA; nucleic acid synthesis ...
    ≥98%
  • T5604

    Tobramycin, Free Base

    Aminoglycoside; protein translation inhibitor.
    ≥98%