Description
AZ-5104 is an active metabolite of AZD-9291 (osimertinib), an inhibitor of EGFR. It has shown efficacy in models of non-small cell lung cancer. TEST!!!!!!
AZ-5104
Product ID A980005
Cas No. 1421373-98-9
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 1421373-98-9 |
|---|---|
| Purity | ≥98% |
| Formula | C27H31N7O2 |
| Formula Wt. | 485.59 |
| IUPAC Name | N-(2-{[2-(Dimethylamino)ethyl](methyl)amino}-5-{[4-(1H-indol-3-yl)-2-pyrimidinyl]amino}-4-methoxyphenyl)acrylamide |
| Synonym | AZ-5104, AZ 5104, AZ5104 |
Shipping and Storage
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Yates J. Ashton S., et al. Irreversible Inhibition of EGFR: Modeling the Combined Pharmacokinetic-Pharmacodynamic Relationship of Osimertinib and Its Active Metabolite AZ5104. Mol Cancer Ther. 15(10):2378-87 (2016). PMID: 27439477.