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Sulbactam is a β-lactamase inhibitor that is administered clinically to improve the efficacy of carbapenem antibiotics. Sulbactam is often administered to improve antibacterial efficacy against Enterobacter and Staphylococcus. TEST!!!!!!
| Cas No. | 68373-14-8 |
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| Purity | ≥98% |
| Formula | C8H11NO5S |
| Formula Wt. | 233.25 |
| Chemical Name | (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| IUPAC Name | (2S,5R)-3,3-dimethyl-4,4, 7-trioxo-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| Synonym | CP 45899 |
| Melting Point | 148-151°C |
| Solubility | Soluble in water, DMSO, ethanol, methanol, DMF. |
| Appearance | Light Orange Powder |
| Store Temp | 4°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Li R, Liao JM, Gu CR, et al. Theoretical investigation on reaction of sulbactam with wild-type SHV-1 β-lactamase: acylation, tautomerization, and deacylation. J Phys Chem B. 2011 Sep 1;115(34):10298-310. PMID: 21797222.
Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010 Jan;23(1):160-201. PMID: 20065329.